From Reykjavík
About 650 km or 8 hour drive.
A domestic airport is also located in the town of Egilsstadir and a flight from Reykjavík is only one hour.
From Akureyri
About 260 km or 3 hour drive. Take a left turn on to road 925 just before entering the town from the north.
From Egilsstaðir
Only 5 minute drive from the center.